Product Data Sheet

Amiloride HCl

Catalog No. A10064

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Amiloride hydrochloride is a Na+ channel blocker, also inhibits TRPP3 channels and Na+/H+ exchanger (NHE).
Adooq's Amiloride HCl has been cited by 2 publications
  • Yu Y, .et al. , Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
  • Thomas D. Williams, .et al. , J Cell Sci, 2018, Mar 15; 131(6): jcs213736 PMID: 29440238
  • Chemical Information
    Catalog Num A10064
    M. Wt 266.1
    Formula C6H9Cl2N7O
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 2016-88-8
    Synonyms MK 870, Midamor, Colectril, Amipramizide, Guanamprazine hydrochloride
    SMILES C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Amiloride hydrochloride is a Na+ channel blocker, also inhibits TRPP3 channels and Na+/H+ exchanger (NHE).
    Solubility
    In vitro DMSO 49 mg/mL (184.15 mM)
    Water 6 mg/mL (22.54 mM)
    Ethanol 5 mg/mL (18.79 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 37.58 mL 187.9 mL 375.8 mL
    0.5 mM 7.52 mL 37.58 mL 75.16 mL
    1 mM 3.76 mL 18.79 mL 37.58 mL
    5 mM 0.75 mL 3.76 mL 7.52 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.