Product Data Sheet

Di-4-ANEPPS

Catalog No. A10079

main product photo
Di-4-ANEPPS is a voltage-sensitive dye that targets voltage-gated ion channels, primarily inhibiting sodium currents. This compound alters fluorescence properties in response to changes in membrane potential, facilitating the examination of ion channel function. It is useful in cardiovascular research, particularly in studies involving electrophysiology of cardiomyocytes, myocardial ischemia, and investigating drug effects on cardiac cells. Di-4-ANEPPS is instrumental in assessing drug cardiotoxicity and elucidating the mechanisms underlying arrhythmias.
Chemical Information
Catalog NumA10079
M. Wt480.66
FormulaC28H36N2O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.90134-00-2
Synonyms
SMILESO=S(CCC[N+]1=CC=C(/C=C/C2=CC=C3C=C(N(CCCC)CCCC)C=CC3=C2)C=C1)([O-])=O
Biological Activity
DescriptionDi-4-ANEPPS is a voltage-sensitive dye that targets voltage-gated ion channels, primarily inhibiting sodium currents. This compound alters fluorescence properties in response to changes in membrane potential, facilitating the examination of ion channel function. It is useful in cardiovascular research, particularly in studies involving electrophysiology of cardiomyocytes, myocardial ischemia, and investigating drug effects on cardiac cells. Di-4-ANEPPS is instrumental in assessing drug cardiotoxicity and elucidating the mechanisms underlying arrhythmias.
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SHIPPING AND STORAGE
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