Di-4-ANEPPS
Catalog No. A10079

Di-4-ANEPPS is a voltage-sensitive dye that targets voltage-gated ion channels, primarily inhibiting sodium currents. This compound alters fluorescence properties in response to changes in membrane potential, facilitating the examination of ion channel function. It is useful in cardiovascular research, particularly in studies involving electrophysiology of cardiomyocytes, myocardial ischemia, and investigating drug effects on cardiac cells. Di-4-ANEPPS is instrumental in assessing drug cardiotoxicity and elucidating the mechanisms underlying arrhythmias.
Chemical Information
| Catalog Num | A10079 |
|---|---|
| M. Wt | 480.66 |
| Formula | C28H36N2O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 90134-00-2 |
| Synonyms | |
| SMILES | O=S(CCC[N+]1=CC=C(/C=C/C2=CC=C3C=C(N(CCCC)CCCC)C=CC3=C2)C=C1)([O-])=O |
Biological Activity
| Description | Di-4-ANEPPS is a voltage-sensitive dye that targets voltage-gated ion channels, primarily inhibiting sodium currents. This compound alters fluorescence properties in response to changes in membrane potential, facilitating the examination of ion channel function. It is useful in cardiovascular research, particularly in studies involving electrophysiology of cardiomyocytes, myocardial ischemia, and investigating drug effects on cardiac cells. Di-4-ANEPPS is instrumental in assessing drug cardiotoxicity and elucidating the mechanisms underlying arrhythmias. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


