Product Data Sheet

AZD6482

Catalog No. A10112

main product photo
AZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy.
Adooq's AZD6482 has been cited by 1 publications
  • Kevin J Pridham, .et al. , iScience, 2024, May 7;27(6):109921 PMID: 38812542
  • Chemical Information
    Catalog NumA10112
    M. Wt408.5
    FormulaC22H24N4O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1173900-33-8
    Synonyms
    SMILESCC1=CN2C(=O)C=C(N=C2C(=C1)[C@@H](C)NC3=CC=CC=C3C(=O)O)N4CCOCC4
    Biological Activity
    DescriptionAZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO74 mg/mL (181.16 mM)
    WaterInsoluble
    Ethanol9 mg/mL (22.03 mM)
    In vivo30% PEG400+0.5% Tween80+5% propylene glycol28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM24.48 mL122.4 mL244.8 mL
    0.5 mM4.9 mL24.48 mL48.96 mL
    1 mM2.45 mL12.24 mL24.48 mL
    5 mM0.49 mL2.45 mL4.9 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.