Product Data Sheet

Belinostat (PXD101)

Catalog No. A10122

main product photo
Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
Adooq's Belinostat (PXD101) has been cited by 1 publications
  • Shariful Islam, .et al. , Blood Adv, 2020, 4(20): 5297-5310 PMID: 33108458
  • Chemical Information
    Catalog NumA10122
    M. Wt318.4
    FormulaC15H14N2O4S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.414864-00-9
    SynonymsPX105684
    SMILESC1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
    Biological Activity
    DescriptionBelinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO56 mg/mL (175.9 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo2% DMSO+30% PEG 300+ddH2O9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM31.41 mL157.04 mL314.07 mL
    0.5 mM6.28 mL31.41 mL62.81 mL
    1 mM3.14 mL15.7 mL31.41 mL
    5 mM0.63 mL3.14 mL6.28 mL
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    SHIPPING AND STORAGE
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