Product Data Sheet

BIBR 1532

Catalog No. A10140

main product photo

BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).

Adooq's BIBR 1532 has been cited by 1 publications
  • Hosoi T, .et al. , Neurosci Lett, 2016, Aug 26;629:241-244 PMID: 27443785
  • Chemical Information
    Catalog NumA10140
    M. Wt331.4
    FormulaC21H17NO3
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.321674-73-1
    Synonyms
    SMILESC/C(=C\C(=O)NC1=CC=CC=C1C(=O)O)/C2=CC3=CC=CC=C3C=C2
    Biological Activity
    Description

    BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).

    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO58 mg/mL (175.03 mM)
    WaterInsoluble
    Ethanol3 mg/mL (9.05 mM)
    In vivo5% DMSO+corn oil9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM30.18 mL150.88 mL301.75 mL
    0.5 mM6.04 mL30.18 mL60.35 mL
    1 mM3.02 mL15.09 mL30.18 mL
    5 mM0.6 mL3.02 mL6.04 mL
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    SHIPPING AND STORAGE
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