Product Data Sheet

Calcitriol (Rocaltrol)

Catalog No. A10173

main product photo
Calcitriol (Rocaltrol) increases blood calcium levels ( [Ca2+] ) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium thus reducing the loss of calcium in the urine.
Chemical Information
Catalog Num A10173
M. Wt 416.6
Formula C27H44O3
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 32222-06-3
Synonyms Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol, 1,25-dihydroxycholecalciferol, 1,25-dihydroxyvitamin D3
SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription Calcitriol (Rocaltrol) increases blood calcium levels ( [Ca2+] ) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium thus reducing the loss of calcium in the urine.
Targets
Target Value
Solubility
In vitro DMSO 79 mg/mL (189.61 mM)
Water Insoluble
Ethanol 79 mg/mL (189.61 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24 mL 120.02 mL 240.04 mL
0.5 mM 4.8 mL 24 mL 48.01 mL
1 mM 2.4 mL 12 mL 24 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.