CCT129202
Catalog No. A10184
CCT129202 is a representative of a structurally novel series of imidazopyridine small-molecule inhibitors of Aurora kinase activity. It shows high selectivity for the Aurora kinases over a panel of other kinases tested and inhibits proliferation in multiple cultured human tumor cell lines.
Catalog Num | A10184 |
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M. Wt | 497 |
Formula | C23H25ClN8OS |
Purity | >98% |
Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
CAS No. | 942947-93-5 |
Synonyms | |
SMILES | CN(C)C1=CC=C(C=C1)C2=NC3=NC=C(C(=C3N2)N4CCN(CC4)CC(=O)NC5=NC=CS5)Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Discription | CCT129202 is a representative of a structurally novel series of imidazopyridine small-molecule inhibitors of Aurora kinase activity. It shows high selectivity for the Aurora kinases over a panel of other kinases tested and inhibits proliferation in multiple cultured human tumor cell lines. |
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Targets |
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In vitro (25°C) | DMSO | 3 mg/mL (6.03 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.12 mL | 100.6 mL | 201.21 mL |
0.5 mM | 4.02 mL | 20.12 mL | 40.24 mL |
1 mM | 2.01 mL | 10.06 mL | 20.12 mL |
5 mM | 0.4 mL | 2.01 mL | 4.02 mL |
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