Product Data Sheet

Cisplatin

Catalog No. A10221

main product photo
Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
Adooq's Cisplatin has been cited by 10 publications
  • Jintian Song, .et al. , J Cancer, 2023, May 21;14(9):1515-1530 PMID: 37325046
  • Huan Li, Srinivas Chatla, .et al. , Res Sq, 2023, Apr 6;rs.3.rs-2688694 PMID: 37066268
  • Min-Yung Kuo, .et al. , Int J Mol Sci, 2022, Dec 21;24(1):138 PMID: 36613579
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • RUI-NING LIANG, .et al. , Research Square, 2022, July 6th
  • Wei Zeng, .et al. , Exp Ther Med, 2021, May; 21(5): 424 PMID: 33747163
  • Yi-Ru Pan, .et al. , Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492
  • Amnah Alshangiti, .et al. , Neuronal Signal, 2019, 2019
  • Calhelha RC, .et al. , Analyst, 2017, Oct 23;142(21):4124-4141 PMID: 28991301
  • Pi-Lin Sung, .et al. , Oncotarget, 2016, Jan 26; 7(4): 4036-4047 PMID: 26716408
    • Chemical Information
    Catalog Num A10221
    M. Wt 300.1
    Formula Cl2H4N2Pt
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 15663-27-1
    Synonyms cisplatinum, CDDP, cis-diamminedichloroplatinum(II)
    SMILES N.N.Cl[Pt+2]Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
    Targets
    Target Value
    Solubility
    In vitro DMSO 56 mg/mL (186.63 mM)
    Water DMF: 11 mg/mL (36.66 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 33.32 mL 166.61 mL 333.22 mL
    0.5 mM 6.66 mL 33.32 mL 66.64 mL
    1 mM 3.33 mL 16.66 mL 33.32 mL
    5 mM 0.67 mL 3.33 mL 6.66 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.