Product Data Sheet

Cyclosporin A

Catalog No. A10260

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Cyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.
Adooq's Cyclosporin A has been cited by 3 publications
  • X Jia, .et al. , J Hazard Mater, 2020, Jun 4;399:123034 PMID: 32544768
  • Y Huang, .et al. , Experimental and Therapeutic Medicine, 2020, 20(2), 736-747 PMID: 32742319
  • Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467
  • Chemical Information
    Catalog NumA10260
    M. Wt1202.6
    FormulaC62H111N11O12
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.59865-13-3
    SynonymsCiclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,
    SMILESCC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
    Biological Activity
    DescriptionCyclosporin A (Cyclosporine A) is an immunosuppressant agent widely used in post-allogeneic organ transplant to reduce the activity of the immune system.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSOWarmed: 99 mg/mL (82.32 mM)
    WaterInsoluble
    EthanolWarmed: 99 mg/mL (82.32 mM)
    In vivo2% DMSO+30% PEG 300+5% Tween 80+ddH2O4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM8.32 mL41.58 mL83.15 mL
    0.5 mM1.66 mL8.32 mL16.63 mL
    1 mM0.83 mL4.16 mL8.32 mL
    5 mM0.17 mL0.83 mL1.66 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.