Product Data Sheet

Dapagliflozin (BMS512148)

Catalog No. A10285

main product photo
Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
Adooq's Dapagliflozin (BMS512148) has been cited by 6 publications
  • Tingting Ding, .et al. , J Diabetes Complications, 2024, Dec 9;39(2):108930 PMID: 39673870
  • David Papadopoli, .et al. , Neoplasia, 2021, Apr;23(4):391-399 PMID: 33784591
  • Neil Tanday, .et al. , Biochem Pharmacol, 2020, Jul;177:114009 PMID: 32360307
  • Subramaniam M, .et al. , Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628
  • Marina Subramaniam, .et al. , Physiol Rep, 2019, May; 7(9): e14090 PMID: 31062524
  • Angelopoulou A, .et al. , AAPS PharmSciTech, 2018, Feb;19(2):621-633 PMID: 8924948
  • Chemical Information
    Catalog NumA10285
    M. Wt408.9
    FormulaC21H25ClO6
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.461432-26-8
    Synonyms
    SMILESCCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Cl
    Biological Activity
    DescriptionDapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
    Solubility
    In vitro (25°C) DMSO75 mg/mL (183.43 mM)
    WaterInsoluble
    Ethanol15 mg/mL (36.68 mM)
    In vivo5% DMSO+40%PEG300+5% tween80+50% H2O3.8 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM24.46 mL122.28 mL244.56 mL
    0.5 mM4.89 mL24.46 mL48.91 mL
    1 mM2.45 mL12.23 mL24.46 mL
    5 mM0.49 mL2.45 mL4.89 mL
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