Product Data Sheet

Decitabine

Catalog No. A10292

main product photo
Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
Adooq's Decitabine has been cited by 5 publications
  • Tianxing Ying, .et al. , Cancers (Basel), 2022, Dec 30;15(1):243 PMID: 36612238
  • Borbala Szabo, .et al. , J Clin Endocrinol Metab, 2022, Sep 5;dgac496 PMID: 36059148
  • Sangni Qian, .et al. , Clin Epigenetics, 2022, Sep 5;14(1):111 PMID: 36064442
  • Borb??la Szab??, .et al. , J Clin Endocrinol Metab, 2020, Jun 1;105(6):dgaa156 PMID: 32232382
  • Bracha Shraibman, .et al. , Mol Cell Proteomics, 2016, Sep; 15(9): 3058-3070 PMID: 27412690
  • Chemical Information
    Catalog NumA10292
    M. Wt228.2
    FormulaC8H12N4O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.2353-33-5
    SynonymsDacogen, 5-Aza-dC
    SMILESC1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O
    Biological Activity
    DescriptionDecitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO44 mg/mL (192.8 mM)
    Water10 mg/mL (43.81 mM)
    EthanolInsoluble
    In vivowater9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM43.82 mL219.11 mL438.21 mL
    0.5 mM8.76 mL43.82 mL87.64 mL
    1 mM4.38 mL21.91 mL43.82 mL
    5 mM0.88 mL4.38 mL8.76 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.