Product Data Sheet

Docetaxel (Taxotere)

Catalog No. A10326

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Docetaxel (Taxotere) is an antineoplastic agent that acts by disrupting the microtubular network in cells that is essential for mitotic and interphase cellular functions.
Adooq's Docetaxel (Taxotere) has been cited by 2 publications
  • Seungyeon Ryu, .et al. , Breast Cancer Res, 2025, Jun 23;27(1):113 PMID: 40551232
  • Adi Jacob Berger, .et al. , Nat Cancer, 2021, 2, 1055-1070 PMID: 35121883
  • Chemical Information
    Catalog NumA10326
    M. Wt807.9
    FormulaC43H53NO14
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.114977-28-5
    SynonymsTaxotere
    SMILESCC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
    Biological Activity
    DescriptionDocetaxel (Taxotere) is an antineoplastic agent that acts by disrupting the microtubular network in cells that is essential for mitotic and interphase cellular functions.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO92 mg/mL (113.88 mM)
    WaterInsoluble
    EthanolWarmed: 49 mg/mL (60.65 mM)
    In vivo5% DMSO+30% PEG 300+5% Tween 80+ddH2O1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM12.38 mL61.89 mL123.78 mL
    0.5 mM2.48 mL12.38 mL24.76 mL
    1 mM1.24 mL6.19 mL12.38 mL
    5 mM0.25 mL1.24 mL2.48 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.