Product Data Sheet

Dutasteride (Avodart)

Catalog No. A10338

main product photo
Dutasteride is a dual 5-a reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).
Adooq's Dutasteride (Avodart) has been cited by 3 publications
  • Makoto Ishikawa, .et al. , Sci Rep, 2018, 8: 12851 PMID: 30150786
  • Makoto Ishikawa, .et al. , Neuropharmacology, 2016, Dec; 111: 142-159 PMID: 27596950
  • Makoto Ishikawa, .et al. , Invest Ophthalmol Vis Sci, 2014, 55(12): 8531-8541 PMID: 25406290
  • Chemical Information
    Catalog NumA10338
    M. Wt528.5
    FormulaC27H30F6N2O2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.164656-23-9
    Synonyms
    SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C
    Biological Activity
    DescriptionDutasteride is a dual 5-a reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO57 mg/mL (107.84 mM)
    WaterInsoluble
    Ethanol6 mg/mL (11.35 mM)
    In vivo2% DMSO+30% PEG 300+2% Tween 80+ddH2O3 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM18.92 mL94.61 mL189.21 mL
    0.5 mM3.78 mL18.92 mL37.84 mL
    1 mM1.89 mL9.46 mL18.92 mL
    5 mM0.38 mL1.89 mL3.78 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.