Product Data Sheet

Loperamide hydrochloride

Catalog No. A10536

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Loperamide hydrochloride is an opioid receptor agonist that functions primarily as an autophagy inducer. This compound selectively inhibits human intestinal carboxylesterases (hiCE), contributing to its anti-diarrheal properties. Its unique mechanism of action makes Loperamide hydrochloride a valuable reagent for studies related to gastrointestinal motility and autophagy modulation in various biological contexts.
Chemical Information
Catalog NumA10536
M. Wt513.50
FormulaC29H34Cl2N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.34552-83-5
SynonymsR-18553 hydrochloride
SMILESO=C(N(C)C)C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.Cl
Biological Activity
DescriptionLoperamide hydrochloride is an opioid receptor agonist that functions primarily as an autophagy inducer. This compound selectively inhibits human intestinal carboxylesterases (hiCE), contributing to its anti-diarrheal properties. Its unique mechanism of action makes Loperamide hydrochloride a valuable reagent for studies related to gastrointestinal motility and autophagy modulation in various biological contexts.
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