Product Data Sheet

LY335979 (Zosuquidar 3HCl)

Catalog No. A10549

main product photo
LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.
Adooq's LY335979 (Zosuquidar 3HCl) has been cited by 1 publications
  • Leo Shen, .et al. , Sci Rep, 2021, Sep 16;11(1):18516 PMID: 34531456
  • Chemical Information
    Catalog NumA10549
    M. Wt637
    FormulaC32H31F2N3O2.3HCl
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.167465-36-3
    SynonymsRS-33295-198
    SMILESC1CN(CCN1C[C@H](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[C@H]6[C@H](C6(F)F)C7=CC=CC=C47.Cl.Cl.Cl
    Biological Activity
    DescriptionLY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO93 mg/mL (145.99 mM)
    Water21 mg/mL (32.96 mM)
    EthanolInsoluble
    In vivo30% PEG400+0.5% Tween80+5% propylene glycol28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM15.7 mL78.49 mL156.99 mL
    0.5 mM3.14 mL15.7 mL31.4 mL
    1 mM1.57 mL7.85 mL15.7 mL
    5 mM0.31 mL1.57 mL3.14 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.