Product Data Sheet

MC1568

Catalog No. A10560

main product photo
MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase, resulting in the death of breast cancer cells by apoptosis.
Adooq's MC1568 has been cited by 4 publications
  • Vivek Bora, .et al. , Can J Physiol Pharmacol, 2021, 6 October
  • Minoru Ueda, .et al. , Plant Physiol, 2017, Dec; 175(4): 1760-1773 PMID: 29018096
  • S Ishikawa, .et al. , Int J Cancer., 2014, 135(11): 2528-2536 PMID: 24346863
  • Usui T, .et al. , Hypertension., 2014, Feb;63(2):397-403 PMID: 24166750
  • Chemical Information
    Catalog Num A10560
    M. Wt 314.3
    Formula C17H15FN2O3
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 852475-26-4
    Synonyms
    SMILES CN1C=C(C=C1/C=C/C(=O)NO)/C=C/C(=O)C2=CC(=CC=C2)F
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase, resulting in the death of breast cancer cells by apoptosis.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO 12 mg/mL (38.18 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% CMC 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.82 mL 159.08 mL 318.17 mL
    0.5 mM 6.36 mL 31.82 mL 63.63 mL
    1 mM 3.18 mL 15.91 mL 31.82 mL
    5 mM 0.64 mL 3.18 mL 6.36 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.