Product Data Sheet

MGCD0103 (Mocetinostat)

Catalog No. A10586

main product photo
MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
Adooq's MGCD0103 (Mocetinostat) has been cited by 2 publications
  • Mari Ishigami-Yuasa, .et al. , Biol Pharm Bull, 2019, 42, 448-452 PMID: 30828077
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
  • Chemical Information
    Catalog Num A10586
    M. Wt 396.4
    Formula C23H20N6O
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 726169-73-9
    Synonyms
    SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO 12 mg/mL (30.27 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% Propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.23 mL 126.14 mL 252.27 mL
    0.5 mM 5.05 mL 25.23 mL 50.45 mL
    1 mM 2.52 mL 12.61 mL 25.23 mL
    5 mM 0.5 mL 2.52 mL 5.05 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.