Product Data Sheet
Monobenzone
Catalog No. A10604
Monobenzone is a potent skin depigmenting agent that primarily targets the enzyme ribonucleotide reductase (RNR) by inhibiting its regulatory subunit, RRM2. It effectively induces depigmentation, making it a valuable compound in vitiligo research. Additionally, Monobenzone demonstrates significant anti-leukemic properties, inhibiting the proliferation and DNA synthesis of acute myeloid leukemia (AML) cells, and promoting cell cycle arrest and apoptosis. These dual functionalities position Monobenzone as a critical reagent in both dermatological and oncology studies.
Chemical Information
| Catalog Num | A10604 |
|---|---|
| M. Wt | 200.24 |
| Formula | C13H12O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 103-16-2 |
| Synonyms | Benoquin |
| SMILES | OC1=CC=C(C=C1)OCC2=CC=CC=C2 |
Biological Activity
| Description | Monobenzone is a potent skin depigmenting agent that primarily targets the enzyme ribonucleotide reductase (RNR) by inhibiting its regulatory subunit, RRM2. It effectively induces depigmentation, making it a valuable compound in vitiligo research. Additionally, Monobenzone demonstrates significant anti-leukemic properties, inhibiting the proliferation and DNA synthesis of acute myeloid leukemia (AML) cells, and promoting cell cycle arrest and apoptosis. These dual functionalities position Monobenzone as a critical reagent in both dermatological and oncology studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
