Product Data Sheet

Nobiletin (Hexamethoxyflavone)

Catalog No. A10651

main product photo
Nobiletin is a chemical compound. It is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. Nobiletin was found to have anti-inflammatory and anti-tumor invasion, proliferation, and metastasis in vitro and in vivo. Nobiletin was also found to potentially inhibit cartilage degradation.
Adooq's Nobiletin (Hexamethoxyflavone) has been cited by 2 publications
  • Siyu Zhu, .et al. , Toxicol Appl Pharmacol, 2025, Jul:500:117380 PMID: 40348029
  • Yi-Hsin Lo, .et al. , Biomedicines, 2022, Mar 3;10(3):595 PMID: 35327397
  • Chemical Information
    Catalog NumA10651
    M. Wt402.4
    FormulaC21H22O8
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.478-01-3
    SynonymsHexamethoxyflavone
    SMILESCOC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC
    Biological Activity
    DescriptionNobiletin is a chemical compound. It is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. Nobiletin was found to have anti-inflammatory and anti-tumor invasion, proliferation, and metastasis in vitro and in vivo. Nobiletin was also found to potentially inhibit cartilage degradation.
    Targets
    TargetValue
    Solubility
    In vitro DMSO70 mg/mL (173.95 mM)
    WaterInsoluble
    Ethanol3 mg/mL (7.45 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM24.85 mL124.25 mL248.51 mL
    0.5 mM4.97 mL24.85 mL49.7 mL
    1 mM2.49 mL12.43 mL24.85 mL
    5 mM0.5 mL2.49 mL4.97 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.