Product Data Sheet

Orlistat

Catalog No. A10676

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Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.  Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity. Anti-atherosclerotic effect. 

Adooq's Orlistat has been cited by 1 publications
  • M Sugihara, .et al. , J Cell Biol, 2019, pii: jcb.201712120 PMID: 30705059
  • Chemical Information
    Catalog NumA10676
    M. Wt495.73
    FormulaC29H53NO5
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.96829-58-2
    SynonymsTetrahydrolipstatin
    SMILESCCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
    Biological Activity
    Description

    Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.  Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity. Anti-atherosclerotic effect. 

    Solubility
    In vitro (25°C) DMSO97 mg/mL (195.67 mM)
    WaterInsoluble
    Ethanol97 mg/mL (195.67 mM)
    In vivo5% DMSO+40% PEG 300+5% Tween 80+ddH2O12 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM20.17 mL100.86 mL201.72 mL
    0.5 mM4.03 mL20.17 mL40.34 mL
    1 mM2.02 mL10.09 mL20.17 mL
    5 mM0.4 mL2.02 mL4.03 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.