Product Data Sheet

Perifosine (NSC-639966)

Catalog No. A10709

main product photo
Perifosine (also KRX-0401) acts as an Akt inhibitor and a PI3K inhibitor.
Adooq's Perifosine (NSC-639966) has been cited by 5 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Bjune K, .et al. , PLoS One, 2019, Jun 19;14(6):e0218537 PMID: 31216345
  • Kyoung-Jae Won, .et al. , Cell Death Dis, 2017, Jan; 8(1): e2554 PMID: 28079882
  • Zhipeng Li, .et al. , Oncotarget, 2016, May 31; 7(22): 31892-31906 PMID: 26895469
  • Won KJ, .et al. , Apoptosis., 2014, Jan;19(1):179-90 PMID: 24085402
  • Chemical Information
    Catalog NumA10709
    M. Wt461.7
    FormulaC25H52NO4P
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.157716-52-4
    SynonymsKRX-0401
    SMILESCCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C
    Biological Activity
    DescriptionPerifosine (also KRX-0401) acts as an Akt inhibitor and a PI3K inhibitor.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSOInsoluble
    Water85 mg/mL (184.11mM)
    Ethanol85 mg/mL (184.11mM)
    In vivowater7 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM21.66 mL108.3 mL216.59 mL
    0.5 mM4.33 mL21.66 mL43.32 mL
    1 mM2.17 mL10.83 mL21.66 mL
    5 mM0.43 mL2.17 mL4.33 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.