Product Data Sheet

Phloretin (Dihydronaringenin)

Catalog No. A10723

main product photo
Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.
Adooq's Phloretin (Dihydronaringenin) has been cited by 1 publications
  • Subramaniam M, .et al. , Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628
    • Chemical Information
    Catalog Num A10723
    M. Wt 274.3
    Formula C15H14O5
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 60-82-2
    Synonyms Dihydronaringenin, Phloretol
    SMILES C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside phlorizin.
    Targets
    Target Value
    Solubility
    In vitro DMSO 46 mg/mL (167.71 mM)
    Water Insoluble
    Ethanol 46 mg/mL (167.71 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 36.46 mL 182.28 mL 364.56 mL
    0.5 mM 7.29 mL 36.46 mL 72.91 mL
    1 mM 3.65 mL 18.23 mL 36.46 mL
    5 mM 0.73 mL 3.65 mL 7.29 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.