Product Data Sheet

SB939 ( Pracinostat )

Catalog No. A10830

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SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
Adooq's SB939 ( Pracinostat ) has been cited by 1 publications
  • Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
  • Chemical Information
    Catalog NumA10830
    M. Wt358.5
    FormulaC20H30N4O2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.929016-96-6
    SynonymsPracinostat, SB-939
    SMILESCCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)/C=C/C(=O)NO
    Biological Activity
    DescriptionSB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO68 mg/mL (189.68 mM)
    WaterInsoluble
    Ethanol26 mg/mL (72.52 mM)
    In vivo1% DMSO+30% polyethylene glycol+1% Tween 8028 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM27.89 mL139.47 mL278.94 mL
    0.5 mM5.58 mL27.89 mL55.79 mL
    1 mM2.79 mL13.95 mL27.89 mL
    5 mM0.56 mL2.79 mL5.58 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.