Product Data Sheet

SRT1720 HCl

Catalog No. A10862

main product photo
SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.
Adooq's SRT1720 HCl has been cited by 7 publications
  • Eleni Pitsillou, .et al. , Comput Biol Chem, 2020, 89: 107408 PMID: 33137690
  • Jie Ren, .et al. , Sleep Breath, 2018, Nov 8 PMID: 30411173
  • Rowlands BD, .et al. , J Neurochem, 2017, Mar;140(6):903-918 PMID: 27925207
  • Adam Khader, .et al. , J Surg Res, 2017, Nov;219:288-295 PMID: 29078895
  • Adam Khader, .et al. , Crit Care Med, 2016, Aug; 44(8): e651-e663 PMID: 26963320
  • Benjamin D. Rowlands, .et al. , J Neurosci Res., 2015, Jul;93(7):1147-56 PMID: 25677687
  • Khader A, .et al. , Transplantation, 2014, 98(2):148-56 PMID: 24918615
  • Chemical Information
    Catalog NumA10862
    M. Wt506
    FormulaC25H23N7OS.HCl
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1001645-58-4
    SynonymsSRT-1720
    SMILESC1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl
    Biological Activity
    DescriptionSRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.
    Targets
    TargetValue
    Solubility
    In vitro DMSO34 mg/mL (67.19 mM)
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM19.76 mL98.81 mL197.63 mL
    0.5 mM3.95 mL19.76 mL39.53 mL
    1 mM1.98 mL9.88 mL19.76 mL
    5 mM0.4 mL1.98 mL3.95 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.