Product Data Sheet

Streptozotocin (Zanosar)

Catalog No. A10868

main product photo
Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.
Adooq's Streptozotocin (Zanosar) has been cited by 10 publications
  • Zhen Liang, .et al. , Nat Metab, 2023, Jan;5(1):29-40 PMID: 36624157
  • Alemayehu Toma, .et al. , J Exp Pharmacol, 2022, 14: 309-316 PMID: 36317069
  • Andressa Braga, .et al. , Braz J Pharm Sci, 2022, 58: e19674
  • Yuanyuan Du, .et al. , Nat Med, 2022, Feb;28(2):272-282 PMID: 35115708
  • Karemah A. Alatawi, .et al. , Saudi Journal of Biological Sciences, 2021, 25 June
  • D.H. Mhya, .et al. , Asian J Exp Biol Sci, 2019, 12 (2): 164-172
  • Stanley I. R. Okoduwa, .et al. , J Diabetol, 2017, 8(3): 74-85
  • Stanley I. R. Okoduwa, .et al. , Medicines (Basel), 2017, Dec; 4(4): 73 PMID: 29019956
  • Stanley I. R. Okoduwa, .et al. , PLoS One, 2017, 12(1): e0170971 PMID: 28129400
  • Stanley I. R. Okoduwa, .et al. , World J Diabetes, 2016, Dec 15; 7(20): 605-614 PMID: 28031778
  • Chemical Information
    Catalog NumA10868
    M. Wt265.2
    FormulaC8H15N3O7
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.18883-66-4
    SynonymsStreptozocin, Zanosar, STZ
    SMILESCN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
    Biological Activity
    DescriptionStreptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.
    Solubility
    In vitro (25°C) DMSO51 mg/mL (192.29 mM)
    Water51 mg/mL (192.29 mM)
    EthanolInsoluble
    In vivoSaline28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM37.71 mL188.54 mL377.07 mL
    0.5 mM7.54 mL37.71 mL75.41 mL
    1 mM3.77 mL18.85 mL37.71 mL
    5 mM0.75 mL3.77 mL7.54 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.