Product Data Sheet

Tadalafil

Catalog No. A10883

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Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.
Chemical Information
Catalog NumA10883
M. Wt389.4
FormulaC22H19N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.171596-29-5
SynonymsAdcirca, Cialis
SMILESCN1CC(=O)N2C(C1=O)CC3=C(C2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
Biological Activity
DescriptionTadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.
Targets
TargetValue
Solubility
In vitro (25°C) DMSO70 mg/mL (179.76 mM)
WaterInsoluble
EthanolInsoluble
In vivo30% propylene glycol, 5% Tween 80, 65% D5W28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.68 mL128.4 mL256.81 mL
0.5 mM5.14 mL25.68 mL51.36 mL
1 mM2.57 mL12.84 mL25.68 mL
5 mM0.51 mL2.57 mL5.14 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.