Product Data Sheet

Retinoic acid (Tretinoin)

Catalog No. A10944

main product photo
Tretinoin is an endogenous agonist for retinoic acid receptors with IC50 value of 14 nM for RAR-alpha, RAR-beta and RAR-gamma receptors).
Chemical Information
Catalog NumA10944
M. Wt300.4
FormulaC20H28O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.302-79-4
SynonymsRetinoic Acid, ATRA, Vitamin A Acid
SMILESCC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
Biological Activity
DescriptionTretinoin is an endogenous agonist for retinoic acid receptors with IC50 value of 14 nM for RAR-alpha, RAR-beta and RAR-gamma receptors).
Targets
TargetValue
Solubility
In vitro DMSO57 mg/mL (189.74 mM)
WaterInsoluble
Ethanol6 mg/mL (19.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM33.29 mL166.44 mL332.89 mL
0.5 mM6.66 mL33.29 mL66.58 mL
1 mM3.33 mL16.64 mL33.29 mL
5 mM0.67 mL3.33 mL6.66 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.