Product Data Sheet

Vinorelbine (Navelbine)

Catalog No. A10976

main product photo
Vinorelbine is the first 5??NOR semi-synthetic vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus.
Adooq's Vinorelbine (Navelbine) has been cited by 6 publications
  • Bo He, .et al. , EMBO Mol Med, 2025, Mar 26;17(5):1071-1100 PMID: 40140727
  • Pavel Burda, .et al. , Mol Metab, 2024, Oct:88:102016 PMID: 39182842
  • Rotem Ben-Hamo, .et al. , Nat Commun, 2020, 11: 3296
  • Roma Kaul, .et al. , Br J Cancer, 2019, 121, pages611-621 PMID: 31481735
  • Nicholas F. Dybdal-Hargreaves, .et al. , Oncotarget, 2018, Jan 19; 9(5): 5545-5561 PMID: 29464017
  • APRIL L. RISINGER, .et al. , Anticancer Res, 2015, Nov; 35(11): 5845-5850 PMID: 26504006
  • Chemical Information
    Catalog NumA10976
    M. Wt778.9
    FormulaC45H54N4O8
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.71486-22-1
    Synonyms
    SMILESCCC1=C[C@H]2C[C@@](C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC
    Biological Activity
    DescriptionVinorelbine is the first 5??NOR semi-synthetic vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus.
    Solubility
    In vitro DMSO99 mg/mL (91.73 mM)
    WaterWarmed: 99 mg/mL (91.73 mM)
    EthanolWarmed: 99 mg/mL (91.73 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM12.84 mL64.19 mL128.39 mL
    0.5 mM2.57 mL12.84 mL25.68 mL
    1 mM1.28 mL6.42 mL12.84 mL
    5 mM0.26 mL1.28 mL2.57 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.