Product Data Sheet

Y-27632 2HCl

Catalog No. A11001

main product photo
Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
Adooq's Y-27632 2HCl has been cited by 34 publications
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  • Chemical Information
    Catalog Num A11001
    M. Wt 320.3
    Formula C14H21N3O.2HCl
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 146986-50-7, 129830-38-2
    Synonyms
    SMILES C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO Warmed: 61 mg/mL (190.46 mM)
    Water 13 mg/mL (40.59 mM)
    Ethanol Insoluble
    In vivo saline 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.22 mL 156.1 mL 312.21 mL
    0.5 mM 6.24 mL 31.22 mL 62.44 mL
    1 mM 3.12 mL 15.61 mL 31.22 mL
    5 mM 0.62 mL 3.12 mL 6.24 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.