Product Data Sheet

Yohimbine hydrochloride (Antagonil)

Catalog No. A11003

main product photo
Yohimbine hydrochloride (Antagonil) is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively)
Chemical Information
Catalog Num A11003
M. Wt 390.9
Formula C21H26N2O3.HCl
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 65-19-0
Synonyms Antagonil, Yohimbe, Aphrodine hydrochloride, Yohimbine monohydrochloride
SMILES COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription Yohimbine hydrochloride (Antagonil) is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively)
Solubility
In vitro DMSO Warmed: 11 mg/mL (28.13 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.58 mL 127.91 mL 255.82 mL
0.5 mM 5.12 mL 25.58 mL 51.16 mL
1 mM 2.56 mL 12.79 mL 25.58 mL
5 mM 0.51 mL 2.56 mL 5.12 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.