Product Data Sheet

ZSTK474

Catalog No. A11014

main product photo
ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.
Adooq's ZSTK474 has been cited by 1 publications
  • Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
  • Chemical Information
    Catalog NumA11014
    M. Wt417.4
    FormulaC19H21F2N7O2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.475110-96-4
    Synonyms
    SMILESC1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5
    Biological Activity
    DescriptionZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO20 mg/mL (47.91 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo0.5% hydroxyethyl cellulose28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM23.96 mL119.79 mL239.58 mL
    0.5 mM4.79 mL23.96 mL47.92 mL
    1 mM2.4 mL11.98 mL23.96 mL
    5 mM0.48 mL2.4 mL4.79 mL
    RETURN POLICY
    Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.