Product Data Sheet

ZSTK474

Catalog No. A11014

main product photo
ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.
Adooq's ZSTK474 has been cited by 1 publications
  • Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
  • Chemical Information
    Catalog Num A11014
    M. Wt 417.4
    Formula C19H21F2N7O2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 475110-96-4
    Synonyms
    SMILES C1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO 20 mg/mL (47.91 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% hydroxyethyl cellulose 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.96 mL 119.79 mL 239.58 mL
    0.5 mM 4.79 mL 23.96 mL 47.92 mL
    1 mM 2.4 mL 11.98 mL 23.96 mL
    5 mM 0.48 mL 2.4 mL 4.79 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.