Product Data Sheet

BMS-754807

Catalog No. A11059

main product photo
BMS-754807 is an efficacious, orally active growth factor 1 receptor/insulin receptor family-targeted kinase inhibitor that may act in combination with a wide array of established anticancer agents.
Adooq's BMS-754807 has been cited by 1 publications
  • Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961
  • Chemical Information
    Catalog NumA11059
    M. Wt461.5
    FormulaC23H24FN9O
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1001350-96-4
    SynonymsBMS754807, BMS 754807
    SMILESC[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
    Biological Activity
    DescriptionBMS-754807 is an efficacious, orally active growth factor 1 receptor/insulin receptor family-targeted kinase inhibitor that may act in combination with a wide array of established anticancer agents.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO86 mg/mL (186.35 mM)
    WaterInsoluble
    Ethanol86 mg/mL
    In vivo2% DMSO+30% PEG 300+ddH2O4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM21.67 mL108.34 mL216.68 mL
    0.5 mM4.33 mL21.67 mL43.34 mL
    1 mM2.17 mL10.83 mL21.67 mL
    5 mM0.43 mL2.17 mL4.33 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.