Product Data Sheet

PF-04929113 (SNX-5422)

Catalog No. A11074

main product photo
PF-04929113 (SNX-5422) is orally bioavailable heat shock protein 90 (Hsp90) inhibitor.
Adooq's PF-04929113 (SNX-5422) has been cited by 2 publications
  • Henry Aceros, .et al. , Life Sci, 2019, 2019 PMID: 30986447
  • Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
  • Chemical Information
    Catalog NumA11074
    M. Wt521.5
    FormulaC25H30F3N5O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.908115-27-5
    SynonymsPF04929113, SNX5422
    SMILESCC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C
    Biological Activity
    DescriptionPF-04929113 (SNX-5422) is orally bioavailable heat shock protein 90 (Hsp90) inhibitor.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO90 mg/mL (172.57 mM)
    WaterInsoluble
    Ethanol4 mg/mL (7.66 mM)
    In vivo0.5% CMC+0.25% Tween 8023 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM19.18 mL95.88 mL191.75 mL
    0.5 mM3.84 mL19.18 mL38.35 mL
    1 mM1.92 mL9.59 mL19.18 mL
    5 mM0.38 mL1.92 mL3.84 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.