Product Data Sheet

JTC-801

Catalog No. A11076

main product photo
JTC-801 is a selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor.
Adooq's JTC-801 has been cited by 2 publications
  • Lihao Gu, .et al. , Cosmetics, 2017, 4(4), 48
  • Toshio Yawata, .et al. , Mol Cell Biochem, 2016, Jan;411(1-2):201-11 PMID: 26427671
    • Chemical Information
    Catalog Num A11076
    M. Wt 448
    Formula C26H25N3O2.HCl
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 244218-51-7
    Synonyms JTC801
    SMILES CCC1=CC=C(C=C1)OCC2=CC=CC=C2C(=O)NC3=CC4=C(C=C3)N=C(C=C4N)C.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription JTC-801 is a selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor.
    Solubility
    In vitro (25°C) DMSO 88 mg/mL (196.45 mM)
    Water Insoluble
    Ethanol 30 mg/mL (66.97 mM)
    In vivo 0.5% methylcellulose 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.32 mL 111.61 mL 223.21 mL
    0.5 mM 4.46 mL 22.32 mL 44.64 mL
    1 mM 2.23 mL 11.16 mL 22.32 mL
    5 mM 0.45 mL 2.23 mL 4.46 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.