Product Data Sheet

TH-302 (Evofosfamide)

Catalog No. A11144

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TH-302 is a selectively targeting hypoxic regions of solid tumors hypoxia-activated prodrug.
Adooq's TH-302 (Evofosfamide) has been cited by 2 publications
  • Anirudh Sattiraju, .et al. , Immunity, 2023, Aug 8;56(8):1825-1843 PMID: 37451265
  • Anirudh Sattiraju, .et al. , bioRxiv, 2022, March 04
  • Chemical Information
    Catalog NumA11144
    M. Wt449
    FormulaC9H16Br2N5O4P
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.918633-87-1
    SynonymsTH302
    SMILESCN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr
    Biological Activity
    DescriptionTH-302 is a selectively targeting hypoxic regions of solid tumors hypoxia-activated prodrug.
    Solubility
    In vitro (25°C) DMSO80 mg/mL (178.15 mM)
    WaterWarmed: 9 mg/mL (20.03 mM)
    Ethanol80 mg/mL (178.15 mM)
    In vivo30% propylene glycol, 5% Tween 80, 65% D5W28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM22.27 mL111.36 mL222.72 mL
    0.5 mM4.45 mL22.27 mL44.54 mL
    1 mM2.23 mL11.14 mL22.27 mL
    5 mM0.45 mL2.23 mL4.45 mL
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    SHIPPING AND STORAGE
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