Product Data Sheet

PHA-767491

Catalog No. A11164

main product photo

PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.

Adooq's PHA-767491 has been cited by 2 publications
  • Lei Tan, .et al. , Res Vet Sci, 2022, 145: 125-134 PMID: 35190327
  • Qi Li, .et al. , Transl Oncol, 2018, Apr; 11(2): 300-306 PMID: 29413763
  • Chemical Information
    Catalog Num A11164
    M. Wt 213.24
    Formula C12H11N3O
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 845714-00-3
    Synonyms PHA767491
    SMILES C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription

    PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.

    Targets
    Target Value
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    SHIPPING AND STORAGE
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