Product Data Sheet

KW-2478

Catalog No. A11195

main product photo

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

Adooq's KW-2478 has been cited by 1 publications
  • Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
  • Chemical Information
    Catalog NumA11195
    M. Wt574.66
    FormulaC30H42N2O9
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.819812-04-9
    SynonymsKW2478
    SMILESCCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O
    Biological Activity
    Description

    KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO114 mg/mL (198.37 mM)
    WaterInsoluble
    Ethanol3 mg/mL (5.22 mM)
    In vivo30% propylene glycol, 5% Tween 80, 65% D5W9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM17.4 mL87.01 mL174.02 mL
    0.5 mM3.48 mL17.4 mL34.8 mL
    1 mM1.74 mL8.7 mL17.4 mL
    5 mM0.35 mL1.74 mL3.48 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.