Product Data Sheet

PNU-120596

Catalog No. A11203

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PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.
Adooq's PNU-120596 has been cited by 1 publications
  • Hugo R Arias, .et al. , Br J Pharmacol, 2022, Sep 9 PMID: 36082615
  • Chemical Information
    Catalog NumA11203
    M. Wt311.72
    FormulaC13H14ClN3O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.501925-31-1
    SynonymsPNU120596
    SMILESCC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl
    Biological Activity
    DescriptionPNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO53 mg/mL (170.02 mM)
    WaterInsoluble
    Ethanol1 mg/mL (3.2 mM)
    In vivo1% DMSO+30% polyethylene glycol+1% Tween 809 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM32.08 mL160.4 mL320.8 mL
    0.5 mM6.42 mL32.08 mL64.16 mL
    1 mM3.21 mL16.04 mL32.08 mL
    5 mM0.64 mL3.21 mL6.42 mL
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