Product Data Sheet

Entecavir hydrate

Catalog No. A11216

main product photo
Entecavir hydrate is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection.
Adooq's Entecavir hydrate has been cited by 4 publications
  • Masaaki Toyama, .et al. , Antimicrob Agents Chemother, 2022, Jun 21;66(6) PMID: 35604213
  • Toyama M, .et al. , Virus Res, 2019, Oct 2;271:197677 PMID: 31376401
  • Kazumoto Murata, .et al. , Gut, 2018, Feb; 67(2): 362-371 PMID: 27789659
  • Jianfei L, .et al. , Biochem Pharmacol, 2017, Dec 15;146:224-232 PMID: 29038020
    • Chemical Information
    Catalog Num A11216
    M. Wt 295.3
    Formula C12H15N5O3.H2O
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 209216-23-9, 142217-69-4
    Synonyms ETV, Baraclude
    SMILES C=C1[C@@H]([C@H](CC1N2C=NC3=C2NC(=NC3=O)N)O)CO.O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription Entecavir hydrate is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection.
    Targets
    Target Value
    Solubility
    In vitro DMSO 52 mg/mL (176.09 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 33.86 mL 169.32 mL 338.64 mL
    0.5 mM 6.77 mL 33.86 mL 67.73 mL
    1 mM 3.39 mL 16.93 mL 33.86 mL
    5 mM 0.68 mL 3.39 mL 6.77 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.