Product Data Sheet

PF 429242

Catalog No. A11230

main product photo
PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.
Adooq's PF 429242 has been cited by 8 publications
  • Kai Xue, .et al. , Oxid Med Cell Longev, 2021, Nov 26;2021:5710440 PMID: 34873430
  • Tong-bing Wang, .et al. , Cell Death Dis, 2021, Aug; 12(8): 717 PMID: 34285190
  • Shiying Xie, .et al. , Am J Physiol Renal Physiol, 2020, Aug 31 PMID: 32865015
  • Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
  • Hui Fang, .et al. , Am J Physiol Cell Physiol, 2017, Dec 1; 313(6): C632-C643 PMID: 28903918
  • Tsutomu Nakagawa, .et al. , J Biochem, 2016, Apr 1;161(4):369-379 PMID: 28013223
  • Shimada S, .et al. , Virology, 2015, Aug;482:19-27 PMID: 25817401
  • Jan H. Reiling, .et al. , Nat Cell Biol., 2013, 15(12): 1473-1485 PMID: 24185178
    • Chemical Information
    Catalog Num A11230
    M. Wt 409.56
    Formula C25H35N3O2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 947303-87-9
    Synonyms PF-429242, PF429242
    SMILES CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)[C@@H]3CCNC3
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.
    Solubility
    In vitro DMSO 77 mg/mL (188 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.42 mL 122.08 mL 244.16 mL
    0.5 mM 4.88 mL 24.42 mL 48.83 mL
    1 mM 2.44 mL 12.21 mL 24.42 mL
    5 mM 0.49 mL 2.44 mL 4.88 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.