Product Data Sheet

IPI-493

Catalog No. A11272

main product photo
IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM.
Chemical Information
Catalog Num A11272
M. Wt 545.62
Formula C28H39N3O8
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 64202-81-9
Synonyms IPI493; IPI 493; NSC 255109;17-Aminogeldanamycin;17-Amino Geldanamycin;17-Aminodemethoxygeldanamycin;17-Amino-17-demethoxygeldanamycin;
SMILES C[C@H]1C[C@H]([C@H]([C@@H](/C=C(/[C@H]([C@@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)N)/C)OC)OC(=O)N)\C)C)O)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.