Product Data Sheet

FK866

Catalog No. A11279

main product photo
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Adooq's FK866 has been cited by 5 publications
  • Takeshi Katayoshi, .et al. , Sci Rep, 2022, Nov 9;12(1):19040 PMID: 36352014
  • Takeshi Nakamura, .et al. , Shimane Journal of Medical Science, 2022, 38 (2), 59-66
  • Takeshi Katayoshi, .et al. , J Photochem Photobiol B, 2021, Jun 12;221:112238 PMID: 34130091
  • Yool Lee, .et al. , Sci Adv, 2021, 7
  • Peter M LoCoco, .et al. , eLife, 2017, 6: e29626 PMID: 29125463
    • Chemical Information
    Catalog Num A11279
    M. Wt 391.5
    Formula C24H29N3O2
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 658084-64-1
    Synonyms K 22.175, FK-866
    SMILES C1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Biological Activity
    Discription FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO Insoluble
    Water Insoluble
    Ethanol 77 mg/mL (196.67 mM)
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O 3 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.54 mL 127.71 mL 255.43 mL
    0.5 mM 5.11 mL 25.54 mL 51.09 mL
    1 mM 2.55 mL 12.77 mL 25.54 mL
    5 mM 0.51 mL 2.55 mL 5.11 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.