Product Data Sheet

Ixabepilone

Catalog No. A11449

main product photo
Ixabepilone is an epothilone B analog
Adooq's Ixabepilone has been cited by 3 publications
  • Dong-Sheng Cao, .et al. , Eur J Med Chem, 2020, Aug 1;199:112421 PMID: 32428794
  • Hoque M, .et al. , Pharmacol Res, 2018, Aug;134:166-178 PMID: 29944980
  • APRIL L. RISINGER, .et al. , Anticancer Res, 2015, Nov; 35(11): 5845-5850 PMID: 26504006
  • Chemical Information
    Catalog NumA11449
    M. Wt506.7
    FormulaC27H42N2O5S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.219989-84-1
    SynonymsBMS-24755, Azaepothilone , BMS 247550-1
    SMILESC[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C
    Biological Activity
    DescriptionIxabepilone is an epothilone B analog
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO95 mg/mL (187.48 mM)
    WaterInsoluble
    Ethanol95 mg/mL (187.48 mM)
    In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 6 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM19.74 mL98.68 mL197.36 mL
    0.5 mM3.95 mL19.74 mL39.47 mL
    1 mM1.97 mL9.87 mL19.74 mL
    5 mM0.39 mL1.97 mL3.95 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.