Product Data Sheet

Ki 20227

Catalog No. A11472

main product photo
Ki 20227 is an inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R).
Adooq's Ki 20227 has been cited by 1 publications
  • Wensheng Wang, .et al. , J Bone Miner Res, 2017, May; 32(5): 939-950 PMID: 28052488
  • Chemical Information
    Catalog Num A11472
    M. Wt 480.54
    Formula C24H24N4O5S
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 623142-96-1
    Synonyms Ki-20227, Ki20227
    SMILES CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Ki 20227 is an inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R).
    Solubility
    In vitro DMSO 94 mg/mL (195.61 mM)
    Water <1 mg/mL
    Ethanol 3 mg/mL (6.24 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.81 mL 104.05 mL 208.1 mL
    0.5 mM 4.16 mL 20.81 mL 41.62 mL
    1 mM 2.08 mL 10.4 mL 20.81 mL
    5 mM 0.42 mL 2.08 mL 4.16 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.