Product Data Sheet

SCH-527123 (Navarixin)

Catalog No. A11555

main product photo
SCH527123 is a potent and selective antagonist of the human CXCR1 and CXCR2 receptors with IC50 of 42 nM and 3 nM, respectively.
Adooq's SCH-527123 (Navarixin) has been cited by 3 publications
  • Ruijie Zhang, .et al. , Int J Oncol, 2022, May;60(5):50 PMID: 35315502
  • Fu S, .et al. , Int J Oncol, 2018, Jul;53(1):349-357 PMID: 29749433
  • Fu S, .et al. , Anticancer Res, 2018, Nov;38(11):6271-6279 PMID: 30396947
  • Chemical Information
    Catalog NumA11555
    M. Wt397.42
    FormulaC21H23N3O5
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.473727-83-2
    SynonymsSCH 527123, SCH527123
    SMILESCC[C@H](C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
    Biological Activity
    DescriptionSCH527123 is a potent and selective antagonist of the human CXCR1 and CXCR2 receptors with IC50 of 42 nM and 3 nM, respectively.
    Targets
    TargetValue
    Solubility
    In vitro DMSO71 mg/mL (178.65 mM)
    WaterInsoluble
    Ethanol71 mg/mL (178.65 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM25.16 mL125.81 mL251.62 mL
    0.5 mM5.03 mL25.16 mL50.32 mL
    1 mM2.52 mL12.58 mL25.16 mL
    5 mM0.5 mL2.52 mL5.03 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.