Product Data Sheet

Tideglusib

Catalog No. A11592

main product photo
Tideglusib is a GSK-3 inhibitor currently in phase II clinical trials for the treatment of Alzheimer disease and progressive supranuclear palsy
Adooq's Tideglusib has been cited by 1 publications
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • Chemical Information
    Catalog Num A11592
    M. Wt 334.39
    Formula C19H14N2O2S
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 865854-05-3
    Synonyms
    SMILES C1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Tideglusib is a GSK-3 inhibitor currently in phase II clinical trials for the treatment of Alzheimer disease and progressive supranuclear palsy
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO Warmed: 7 mg/mL (20.93 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+corn oil 2.3 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 29.91 mL 149.53 mL 299.05 mL
    0.5 mM 5.98 mL 29.91 mL 59.81 mL
    1 mM 2.99 mL 14.95 mL 29.91 mL
    5 mM 0.6 mL 2.99 mL 5.98 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.