Product Data Sheet

VE-821

Catalog No. A11605

main product photo
VE-821 is a potent and selective inhibitor of protein kinase ATR.
Adooq's VE-821 has been cited by 7 publications
  • Yiovana Veronica Okraine, .et al. , Cell Death Dis, 2025, Jul 8;16(1):503 PMID: 40628724
  • Atsushi Saito, .et al. , Cell Rep, 2023, May 30;42(5):112479 PMID: 37178686
  • Mitsuru Sasaki-Honda, .et al. , Hum Mol Genet, 2018, Dec 1; 27(23): 4024-4035 PMID: 30107443
  • Kim J, .et al. , Mol Cell, 2018, Jan 4;69(1):36-47.e7 PMID: 29249653
  • Antonio Postigo, .et al. , Cell Rep, 2017, May 2; 19(5): 1022-1032 PMID: 28467896
  • Nnennaya Kanu, .et al. , Genome Biol, 2016, 17: 185 PMID: 27634334
  • Carolyn Botting, .et al. , Virol J, 2016, 13: 15 PMID: 26817608
  • Chemical Information
    Catalog NumA11605
    M. Wt368.4
    FormulaC18H16N4O3S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1232410-49-9
    SynonymsVE821
    SMILESCS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N
    Biological Activity
    DescriptionVE-821 is a potent and selective inhibitor of protein kinase ATR.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO65 mg/mL (176.43 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM27.14 mL135.72 mL271.44 mL
    0.5 mM5.43 mL27.14 mL54.29 mL
    1 mM2.71 mL13.57 mL27.14 mL
    5 mM0.54 mL2.71 mL5.43 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.