Product Data Sheet

BAY 80-6946 (Copanlisib)

Catalog No. A11766

main product photo
BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
Adooq's BAY 80-6946 (Copanlisib) has been cited by 2 publications
  • Toshihisa Satta, .et al. , Clin Cancer Res, 2023, Apr 3;29(7):1332-1343 PMID: 36652560
  • Shin SM, .et al. , Sci Adv, 2020, Jan 15;6(3):eaay2174 PMID: 31998840
  • Chemical Information
    Catalog NumA11766
    M. Wt480.2
    FormulaC23H28N8O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1032568-63-0
    SynonymsBAY80-6946, BAY806946
    SMILESCOC1=C(C=CC2=C1N=C(N3C2=NCC3)NC(=O)C4=CN=C(N=C4)N)OCCCN5CCOCC5
    Biological Activity
    DescriptionBAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
    Targets
    TargetValue
    Solubility
    In vitro DMSOInsoluble
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM20.82 mL104.12 mL208.25 mL
    0.5 mM4.16 mL20.82 mL41.65 mL
    1 mM2.08 mL10.41 mL20.82 mL
    5 mM0.42 mL2.08 mL4.16 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.