Product Data Sheet

Prucalopride

Catalog No. A11771

main product photo
Prucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements.
Adooq's Prucalopride has been cited by 1 publications
  • Pierre Meschin, .et al. , Cell Calcium, 2015, Dec;58(6):549-57 PMID: 26427584
  • Chemical Information
    Catalog NumA11771
    M. Wt367.9
    FormulaC18H26ClN3O3
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.179474-81-8
    SynonymsResolor
    SMILESCOCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl
    Biological Activity
    DescriptionPrucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements.
    Targets
    TargetValue
    Solubility
    In vitro DMSO52 mg/mL (141.35 mM)
    WaterInsoluble
    Ethanol33 mg/mL (89.7 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM27.18 mL135.91 mL271.81 mL
    0.5 mM5.44 mL27.18 mL54.36 mL
    1 mM2.72 mL13.59 mL27.18 mL
    5 mM0.54 mL2.72 mL5.44 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.