Product Data Sheet

Cabazitaxel

Catalog No. A11831

main product photo
Cabazitaxel is a semi-synthetic derivative of a natural taxoid. Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment
Adooq's Cabazitaxel has been cited by 2 publications
  • Satoshi Endo, .et al. , J Biochem, 2021, Mar 17 PMID: 33729485
  • Tomohiro Nabekura, .et al. , Biochem Biophys Rep, 2020, Mar; 21: 100727 PMID: 31993509
  • Chemical Information
    Catalog NumA11831
    M. Wt835.93
    FormulaC45H57NO14
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.183133-96-2
    SynonymsTXD-258, XRP 6258
    SMILESCC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
    Biological Activity
    DescriptionCabazitaxel is a semi-synthetic derivative of a natural taxoid. Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment
    Targets
    TargetValue
    Solubility
    In vitro DMSO91 mg/mL (108.85 mM)
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM11.96 mL59.81 mL119.63 mL
    0.5 mM2.39 mL11.96 mL23.93 mL
    1 mM1.2 mL5.98 mL11.96 mL
    5 mM0.24 mL1.2 mL2.39 mL
    RETURN POLICY
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.